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Patel and colleagues found that patients with obsessive compulsive disorder preferred psychotherapy alone over medication by a wide margin 43 percent to 16 percent followed by a combination of psychotherapy and medication 5 3 a number of individuals do not respond to psychotropic medication alone. Antipsychotic medications antipsychotic drugs are typically used to treat psychotic disorders such as schizophrenia antipsychotic medications may also be used to treat bipolar disorders or used with antidepressants to treat depression. The most common medications for psychotic disorders are antipsychotic medications nearly all of them work by blocking dopamine which research shows is overactive in the brains of people with psychotic disorders first generation antipsychotics were developed in the 1950s and effectively treat psychotic symptoms. Psychotherapy is known to be an effective treatment for a wide range of psychological disorders yet even before news of the apa scandal hit the press the average person seeking help has tended